AIMS AND SCOPE

Critical Reviews^TM in Eukaryotic Gene Expression presents timely concepts and experimental approaches that are contributing to rapid advances in our understanding of gene regulation, organization, and structure. The journal provides in-depth critical reviews of the current literature on a well-defined topic of immediate interest, written by recognized specialists in the field. Extensive reference lists accompany all articles, providing a comprehensive information resource. The contributions of molecular, cellular, biochemical, and genetic approaches to eukaryotic gene expression are incorporated into each review. The relationship between gene structure and function is stressed, with emphasis on coordinate control of biological processes. Regulatory mechanisms are explored from the perspective of sequences and regulatory molecules that influence structure and expression of eukaryotic genes, as well as within the context of cellular architecture and its relationship to development of cell specialization and tissue organization.